Copper plays an essential role in the production of collagen, and works with vitamin C to make another connective tissue protein called elastin.  Elastin is important for elasticity and flexibility of the tissue.  It is well established that the maturation of numerous tissue collagens depends on dietary copper.


  1. Opsahl, Zeronian, Ellison et al.  Role of copper in collagen cross-linking and its influence on selected mechanical properties of chick bone and tendon. J. Nutr., Apr 1982; 112: 708 - 716.
  2. Tanzer, M.  Cross-linking of collagen.  Science 180, 561-566.