Silicon is one of the top ten elements in the body and a very important and often overlooked element for construction and healing of connective tissue. There are, in fact, 7 grams of silicon in the body, almost twice the amount of iron. Observational and interventional trials have shown favorable correlations between silicon consumption and the health of bone and connection tissue. Supplemental silicon’s effectiveness in increasing collagen production was demonstrated in a Belgian study that showed an increase in skin collagen content in calves supplemented with silicon. While high levels of silicon in the fetus, this declines dramatically with age, with as much as an 80% decline in the elderly. It is estimated that as much as 15-25 mg of elemental silicon is needed daily for connective tissue maintenance, with up to 40 mg for collagen restructuring, however no formal RDA exists for this element.

Silicon’s effectiveness in increasing collagen production appears to be due to the fact that it is a constituent of the enzyme prolyl hydrolase, which helps the body produce both collagen and gycosaminoglycans, important for connective tissue and joint health. In one study, silicon supplementation increased collagen type I synthesis in cells treated with supplemental silicon. Conversely, the synthesis of collagen decreases in the case of silicon deficiency with studies showing that silicon deprivation decreases collagen formation in wounds and bone. In addition to facilitating collagen production, supplemental silicon has interestingly enough been found to decrease the pain of tendonitis. Finally, silicon and boron combined together have a synergistic effect, that is why you will find both of these essential elements included in LigaGenix.


  1. Si-G5 (Organic Silicon-G5)
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